Resources

Patient Brochure

Take an active role in your care

This booklet will help you know what to expect from treatment with IXEMPRA® (ixabepilone). To get the most from your treatment with IXEMPRA:

  • Stay in touch with your healthcare team.
  • Let them know how you are feeling.
  • Talk with them about any side effects you may have.
  • Ask what you can do that may help you stay on treatment.
Side Effects Tracker

Track and share with your doctor

Use this side effects tracker to record side effects you have and when you have them. Print and complete this tracker for each cycle to track your side effects. Share it with your doctor at each office visit.

Websites
Learn more about metastatic breast cancer, also called mBC

Living Beyond Breast Cancer. Provides programs and services to help people whose lives have been impacted by breast cancer by providing information, community, and support that you can trust, is easy for you to access, and is respectful of you and your situation. lbbc.org

Metastatic Breast Cancer Network (MBCN). A national, independent, nonprofit, all-volunteer, patient-led advocacy organization dedicated to the unique concerns of the women and men living with metastatic breast cancer, also known as stage IV, or advanced, breast cancer. mbcn.org

National Comprehensive Cancer Network (NCCN). A not-for-profit alliance of 27 of the world’s leading cancer centers dedicated to improving the quality, effectiveness, and efficiency of care provided to patients with cancer. nccn.com

Look Good Feel Better. Dedicated to improving the self-esteem and quality of life of people undergoing treatment for cancer. The group’s aim is to improve their self-image and appearance through complimentary group, individual, and self-help beauty sessions that create a sense of support, confidence, courage, and community. lookgoodfeelbetter.org

Susan G. Komen. Provides a wealth of safe, accurate, current, and evidence-based breast cancer information that has been developed with experts in breast cancer. If you want to know more on anything from understanding a diagnosis to treatments to types of assistance and support, you’ll find it here. komen.org

OncoLink. OncoLink was the first cancer information website on the Internet, started in 1994, and remains one of the largest. This award-winning site is maintained by a group of oncology healthcare professionals who understand the needs of patients, caregivers, and healthcare professionals. oncolink.org

Breastcancer.org. This community and its discussion boards have registered members from around the world. You can register to become a member, or you can simply browse the stories, support, and information that is offered. breastcancer.org

Inspire. A safe and secure place for patients and caregivers to support and connect with one another through online health and wellness support communities. Join many others who understand what you’re going through and are making important decisions about their health. inspire.com

CaringBridge. No more repeating the story over and over. Connect with all of your family and friends at once, giving you time to focus on what matters. By creating a free CaringBridge website, people in a time of need can share updates, photos, and videos, connecting with friends and family who care and want to help. caringbridge.org

METAvivor. A volunteer-led, nonprofit organization that funds vital research to help improve the longevity and quality of life for mBC patients, rallying public attention to the urgent needs of the mBC community, helping patients find strength through support and purpose, and making every dollar count to extend and improve quality of life for mBC patients. metavivor.com

CancerCare. Provides telephone, online, and face-to-face counseling, support groups, education, publications, and financial and co-payment assistance. Professional oncology social workers offer personalized care, and all services are free of charge. cancercare.org

Cancer Support Community. Emotional and educational services for all people affected by cancer. This website has a range of information, tools, and support to help you cope with the impact of cancer. cancersupportcommunity.org

Resources

Nurse’s guide to IXEMPRA therapy

This practical guide includes dosing calculations for preparing IXEMPRA® (ixabepilone) for infusion, a review of indications/contraindications, and tables that summarize dose modifications for toxicities and special populations.

Dosing and administration guide

Use this brochure as a quick guide for dosing and administration of IXEMPRA monotherapy and combination therapy with capecitabine.

Pharmacy fact sheet

For a reference for how IXEMPRA is supplied (the 15-mg and 45-mg IXEMPRA Kits), use this pharmacy fact sheet, which includes recommended dosing, premedication, and dose modifications for toxicities and special populations.

Patient brochure

This brochure explains to patients what to expect while being treated with IXEMPRA. This resource lists the indications for IXEMPRA and describes the signs and symptoms of common side effects and the more serious adverse reactions, including peripheral neuropathy, neutropenia, and hypersensitivity.

Ixabepilone Review Article: July 2021

Review of effectiveness, safety, and tolerability. Ixabepilone is approved as monotherapy and in combination with capecitabine for the treatment of metastatic breast cancer in patients with demonstrated resistance to anthracyclines and taxanes. Portions of this article may contain information not included in the approved IXEMPRA labeling.

Study 046: Combination therapy

Ixabepilone Plus Capecitabine for Metastatic Breast Cancer Progressing After Anthracycline and Taxane Treatment. Portions of this journal article may contain information not included in the approved IXEMPRA labeling.

Study 081: Monotherapy

Efficacy and Safety of Ixabepilone (BMS-247550) in a Phase II Study of Patients With Advanced Breast Cancer Resistant to an Anthracycline, a Taxane, and Capecitabine. Portions of this journal article may contain information not included in the approved IXEMPRA labeling.

IXEMPRA combination speaker program deck

View this educational slide deck, which includes an overview of breast cancer and factors associated with poor prognosis, as well as the clinical data for IXEMPRA combination therapy.

IXEMPRA monotherapy speaker program deck

View this educational slide deck, which includes IXEMPRA indications and usage and the clinical data for its use as monotherapy.

Prescriber perspectives

Solving for Treatment Resistance in Metastatic or Locally Advanced Breast Cancer

Play Video

IXEMPRA (Ixabepilone) for advanced triple-negative breast cancer

Play Video

Clinical activity with evolved disease

Play Video

Managing toxicities associated with IXEMPRA

Play Video

Ideal patients for IXEMPRA

Play Video

Indications and Important Safety Informationexpand

What is IXEMPRA® (ixabepilone)?

IXEMPRA is used alone or with another cancer medicine called capecitabine to treat locally advanced breast cancer or breast cancer that has spread to other parts of the body (metastatic) when certain other medicines have not worked or no longer work. It is not known if IXEMPRA is safe and effective in children.

Important Safety Information about IXEMPRA

Your healthcare provider should do blood tests to check your liver function before you begin receiving IXEMPRA and as needed while you are receiving IXEMPRA. If blood tests show that you have liver problems, do not receive injections of IXEMPRA along with the medicine capecitabine. Taking these two medicines together if you have liver problems increases your chance of serious problems. These include serious infection and death due to a very low white blood cell count (neutropenia).

You should not have your injection of IXEMPRA if you:

Before you receive IXEMPRA, tell your healthcare provider about all of your medical conditions, including if you:

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. IXEMPRA and certain other medicines may affect each other causing side effects. IXEMPRA may affect the way other medicines work, and other medicines may affect how IXEMPRA works. Know the medicines you take. Keep a list of your medicines with you to show your healthcare provider.

How will I receive IXEMPRA?

What should I avoid while receiving IXEMPRA?

IXEMPRA may cause serious side effects. Tell your healthcare provider right away if you have any of the following while taking IXEMPRA:

The most common side effects of IXEMPRA when used alone or with capecitabine may include:

IXEMPRA may cause fertility problems in females and males, which may affect your ability to have children. Talk to your healthcare provider if you have concerns about fertility.

If you have any questions about your health or your medicines, talk with your healthcare provider.

Click here to see the Full Prescribing Information, including boxed WARNING regarding liver disease.